P2P Call Guide

How to Win a P2P Call for Chemotherapy / Infusion Therapy Denied by UHC

Payer-specific strategy, medical necessity arguments, and the exact phrases to use when UnitedHealthcare denies Chemotherapy / Infusion Therapy (CPT 96413, 96415, 96417).

Why UHC Denies Chemotherapy / Infusion Therapy

Regimen not first-line per NCCN guidelines

Off-label use without compendia support

Continuation after disease progression not justified

Know UnitedHealthcare's Criteria

UHC uses InterQual criteria and their own Clinical UM Guidelines (CG series). Medical directors are typically accessible for P2P within 5 business days.

Key policies to know:

  • Requires eviCore for MSK and advanced imaging prior auth
  • Clinical UM Guidelines (CG series) are publicly available online
  • Prior auth through Optum/UHG portal
  • Known for strict step therapy requirements on biologics

Building Your Medical Necessity Argument

Cite specific NCCN guideline category and recommendation level

Document prior treatment lines and responses

Reference tumor molecular markers guiding treatment selection

If off-label, cite peer-reviewed evidence or compendia listing

P2P Call Tips for UHC

Reference UHC's own Clinical UM Guideline number (e.g., CG-SURG-71)

UHC medical directors respond well to InterQual criteria language

Be specific about which InterQual subset applies

Have the CG policy number ready -- shows you've done your homework

Guidelines to Reference

  • NCCN Clinical Practice Guidelines by cancer type
  • CMS Anticancer Chemotherapy NCD

Relevant CPT Codes

CPT 96413CPT 96415CPT 96417

Specialty: Oncology

Want the full strategy?

The P2P Playbook covers payer-specific approaches for Chemotherapy / Infusion Therapy denied by UHC -- plus 15 denial objections with word-for-word responses, what reviewers are actually thinking, and the 60-second prep framework. Written by a medical director who reviewed cases for major payers.

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