P2P Call Guide

How to Win a P2P Call for Chemotherapy / Infusion Therapy Denied by Anthem BCBS

Payer-specific strategy, medical necessity arguments, and the exact phrases to use when Anthem / Blue Cross Blue Shield denies Chemotherapy / Infusion Therapy (CPT 96413, 96415, 96417).

Why Anthem BCBS Denies Chemotherapy / Infusion Therapy

Regimen not first-line per NCCN guidelines

Off-label use without compendia support

Continuation after disease progression not justified

Know Anthem / Blue Cross Blue Shield's Criteria

Anthem uses their own Clinical UM Guidelines and AIM Specialty Health for imaging. Medical policy numbers are publicly searchable.

Key policies to know:

  • AIM Specialty Health manages imaging prior auth
  • Clinical UM Guidelines searchable at anthem.com/provider
  • Known for strict imaging prior auth requirements
  • Uses evidence-based medicine approach with published policies

Building Your Medical Necessity Argument

Cite specific NCCN guideline category and recommendation level

Document prior treatment lines and responses

Reference tumor molecular markers guiding treatment selection

If off-label, cite peer-reviewed evidence or compendia listing

P2P Call Tips for Anthem BCBS

Reference specific Anthem Clinical UM Guideline by policy number

For imaging, address AIM criteria specifically

Anthem medical directors appreciate evidence-based arguments

Cite specific clinical criteria being met from their own policy

Guidelines to Reference

  • NCCN Clinical Practice Guidelines by cancer type
  • CMS Anticancer Chemotherapy NCD

Relevant CPT Codes

CPT 96413CPT 96415CPT 96417

Specialty: Oncology

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The P2P Playbook covers payer-specific approaches for Chemotherapy / Infusion Therapy denied by Anthem BCBS -- plus 15 denial objections with word-for-word responses, what reviewers are actually thinking, and the 60-second prep framework. Written by a medical director who reviewed cases for major payers.

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