P2P Call Guide

How to Win a P2P Call for Genetic / Genomic Testing Denied by Anthem BCBS

Payer-specific strategy, medical necessity arguments, and the exact phrases to use when Anthem / Blue Cross Blue Shield denies Genetic / Genomic Testing (CPT 81479, 81455, 81432).

Why Anthem BCBS Denies Genetic / Genomic Testing

Test not considered medically necessary for this diagnosis

Does not meet hereditary cancer testing criteria

Results will not change treatment plan

Know Anthem / Blue Cross Blue Shield's Criteria

Anthem uses their own Clinical UM Guidelines and AIM Specialty Health for imaging. Medical policy numbers are publicly searchable.

Key policies to know:

  • AIM Specialty Health manages imaging prior auth
  • Clinical UM Guidelines searchable at anthem.com/provider
  • Known for strict imaging prior auth requirements
  • Uses evidence-based medicine approach with published policies

Building Your Medical Necessity Argument

Document how test results will directly change management

Meet NCCN testing criteria (family history, age, tumor type)

Reference specific actionable mutations being tested

Note FDA-approved companion diagnostics if applicable

P2P Call Tips for Anthem BCBS

Reference specific Anthem Clinical UM Guideline by policy number

For imaging, address AIM criteria specifically

Anthem medical directors appreciate evidence-based arguments

Cite specific clinical criteria being met from their own policy

Guidelines to Reference

  • NCCN Genetic/Familial High-Risk Assessment Guidelines
  • CMS NCD for Next Generation Sequencing

Relevant CPT Codes

CPT 81479CPT 81455CPT 81432

Specialty: Oncology / Medical Genetics

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